The Effect of Final Irrigation Protocols on the Apical Sealing Ability of Epoxy Resin-based and Bioceramic-based Root Canal Sealers

Aim: This study was designed to investigate the effect of different final irrigation protocols on apical sealing ability bioceramic and epoxy resin-based sealers.
 Materials methods: Thirty human single-rooted mandibular premolars were instrumented using ProTaper Next rotary files. Teeth randomly divided into three groups according regimen; Group I: 5 ml 0.2% CNPs/3 min, II: 2.5 CNPs/1.5 min followed by 17% EDTA/1.5 III: EDTA/3min. All subdivided two subgroups based obturation material; Subgroup A: gutta-percha/Sure-Seal Root BC Sealer B: gutta-percha/AH Plus. canals obturated single cone technique. The assessed modified silver staining technique with ammoniacal nitrate tracer solution. Samples sectioned longitudinally examined scanning electron microscope.
 Results: Sure-Seal sealer showed significantly lower nanoleakage compared AH Plus (p < 0.001). No significant difference recorded in among = 0.284), while a higher EDTA group 0.002). depth penetration dentinal tubules subgroup For both sealers, highest for solution 0.001).
 Conclusions: sealers is better than that sealers. type irrigating seems affect post-obturation seal sealer.
 Keywords: Bioceramic, Plus, Chitosan nanoparticles, EDTA, Sealing ability.